Russell K, Arthur S, Goulet C, Selci E, Morrongiello B. Understanding youths’ attitudes and practices regarding listening to music, video recording and terrain park use while skiing and snowboarding. BMC Pediatrics. 2020; doi:10.1186/s12887-020-02292-6 PMID: 32814547
Russell K, Selci E, Piotrowski C, McFaull S, Richmond S, Snider C. Child injuries in public transport vehicles that do not require restraints. International Journal of Injury Control and Safety Promotion. 2020; 27:347-354. doi:10.1080/17457300.2020.1778039 PMID: 32536254
Piotrowski C, Warda L, Pankratz C, Dubberley K, Russell K, Assam H. Carevic M. The perspectives of young people on barriers to and facilitators of bicycle helmet and booster seat use. Child: Care, Health & Development. 2020; 46(5):591-8. doi: 10.111/cch.12791 PMID: 3252542
Piotrowski V, Warda L, Pankratz V, Dubberley K, Russell K, Assam H, Carevic M. A comparison of parent and child perspectives about barriers to and facilitators of bicycle helmet and booster seat use. International Journal of Injury Control and Safety Promotion. 2020; 27:276-285. doi: 10.1080/17457300.2020.1760308 PMID: 32354275
Olson A, Ellis MJ, Selci E, Russell K. Delayed symptom onset following acute pediatric sport-related concussion. Frontiers in Neurology: Neurotrauma. 2020;11:220 doi.org/10.3389/fneur.2020.00220. eCollection 2020. PMID: 32318012
Fehr K, Moossavi S, Sbihi H, Boutin RCT, Bode L, Robertson B, Yonemitsu C, Field CJ, Becker AB, Mandhane PJ, Sears MR, Khafipour E, Moraes TJ, Subbarao P, Finlay BB, Turvey SE, AZAD MB*. Breastmilk feeding practices are associated with the co-occurrence of bacteria in mothers’ milk and the infant gut: the CHILD Cohort Study. Cell Host & Microbe 2020. DOI: 10.1016/j.chom.2020.06.009 PMID: 32652062
Moossavi S, Fehr K, Derakhshani H, Sbihi H, Robertson B, Bode L, Brook J, Turvey SE, Moraes TJ, Becker AB, Mandhane PJ, Sears MR, Khafipour E, Subbarao P, AZAD MB*. Human milk fungi: environmental determinants and inter-kingdom associations with milk bacteria in the CHILD Cohort Study. BMC Microbiology 2020. DOI: 10.1186/s12866-020-01829-0
Swanson KS, Gibson GR, Hutkins R, Reimer RA, Reid G, Verbeke K, Scott KP, Holscher HD, AZAD MB, Delzenne NM, Sanders ME. The International Scientific Association for Probiotics and Prebiotics (ISAPP) consensus statement on the definition and scope of synbiotics. Nature Reviews Gastroenterology & Hepatology 2020. DOI: https://www.nature.com/articles/s41575-020-0344-2
Kosowan L, Page J, Protudjer J, Williamson T, Queenan J, Singer A. Characteristics associated with pediatric growth measurement collection in electronic medical records: a retrospective observational study. BMC Family Practice. 2020;21:191. https://doi.org/10.1186/s12875-020-01259-x
Singer A, Kosowan L, Soller L, Chan E, Nankissoor N, Phung R, Abrams E. Prevalence of physician-reported food allergy in Canadian children. Journal of Allergy and Clinical Immunology: In Practice. 2020. https://doi.org/10.1016/j.jaip.2020.07.039
SARS-CoV-2 multifaceted interaction with human host. Part I: What we have learnt and done so far, and the still unknown realities. Delcuve GP, Lakowski TM, Su RC, Beacon TH, Davie JR. IUBMB Life. 2020 Sep 12. doi: 10.1002/iub.2380. Online ahead of print. PMID: 32918855 Review.
SARS-CoV-2 multifaceted interaction with the human host. Part II: Innate immunity response, immunopathology, and epigenetics. Beacon TH, Su RC, Lakowski TM, Delcuve GP, Davie JR. IUBMB Life. 2020 Sep 16. doi: 10.1002/iub.2379. Online ahead of print. PMID: 32936531 Review.
Bernstein CN, Walld R, Marrie RA. Social Determinants of Outcomes in Inflammatory Bowel Disease. Am J Gastroenterol. 2020 Aug 5. doi:
Cole, L.K., Meija, E.M., Sparagna, G.C., Vandel, M., Xiang, B., Han, X., Dedousis, N., Kaufman, B. A., Dolinsky, V.W. and HATCH, G.M. (2020) Cardiolipin Deficiency Elevates Susceptibility to a Lipotoxic Hypertrophic Cardiomyopathy. Journal of Molecular and Cellular Cardiology 144, 24-34.
Davis, A., Cole, L.K., Min, K.K-J., Choy, P.C., Mymin, D. and HATCH, G.M. (2020) A phytosterolemic mixture of sterols inhibits cholesterol synthesis, esterification and low-density lipoprotein receptor abundance in HepG2 cells. Lipids. 55, 193-198.
The Office of Educational and Faculty Development recently published a paper in MedEdPublish titled 12 Tips for Pivoting to Teaching in a Virtual Environment. The paper provides strategies, guidance, and advice for instructors in health professions education who are pivoting to teaching in virtual environments as a result of Covid-19.
Rachul, C., Marcon, A. R., Collins, B., & Caulfield, T. (2020, May 19). Covid-19 and “Immune boosting” on the Internet: A content analysis of Google search results. https://doi.org/10.31219/osf.io/q9m4s
Rachul, C., Collins, B., Ahmed, M., & Cai, G. (2020). Twelve tips for designing assignments that foster independence in learning. Medical Teacher. https://doi.org/10.1080/0142159X.2020.1752914
Jones, I., Collins, B., Hamilton, J., & Mawdsley, H. (2020). Initial Employment Patterns for the University of Manitoba’s Master of Physician Assistant Studies (MPAS): 2010-2016. Journal of Canada's Physician Assistants
Dhingra R, Guberman M, Rabinovich-Nikitin I, Gerstein J, Margulets V, Gang H, Thliveris J and Kirshenbaum LA. Impaired NF-kB signalling underlies cyclophilin D-mediated mitochondrial permeability transition pore opening in doxorubicin cardiomyopathy. Cardiovasc Res. 1;116(6):1161-1174; 2020.
Olgar Y, Tuncay E, Degirmenci S, Billur D, Dhingra R, Turan B and Kirshenbaum LA. Ageing-associated increase in SGLT2 disrupts mitochondrial/sarcoplasmic reticulum Ca 2+ homeostasis and promotes cardiac dysfunction. J Mol Cell Cardiol 24(15):8567-8578; 2020.
Sareen N, Abu‐El‐Rub E, Ammar HI, Yan W, Lester Sequiera G, ShamsEldeen AM, Moudgil M, Dhingra R, Shokry HS, Rashed LA, Kirshenbaum LA, Dhingra S. Hypoxia‐induced downregulation of cyclooxygenase 2 leads to the loss of immunoprivilege of allogeneic mesenchymal stem cells. FASEB J.; (Epub) doi: 10.1096/fj.202001478R. 2020
Rabinovich-Nikitin I, Love M, Kirshenbaum LA. Inhibition of MMP Prevents Doxorubicin-Induced Cardiotoxicity by Attenuating Cardiac Intracellular and Extracellular Matrix Remodeling Corresponding, Cardiovasc Res; (In press) 2020
Dhingra R, Rabinovich-Nikitin I, Guberman M, Margulets V, Aguilar F, Gang H and Kirshenbaum LA. Dynamic Regulation of TRAF2 Sensitizes Cardiac Myocytes to TNFα and Doxorubicin Cardiotoxicity. Circ Res; (Submitted) 2020
Rabinovich-Nikitin I, Dhingra R, Martino T and Kirshenbaum LA. Mitochondrial Fitness Is Regulated by Circadian Clock Gene in Cardiac Myocytes. Cell Reports; (Submitted) 2020
Aziz I, McMahon A, Rabinovich-Nikitin I, Kirshenbaum LA, Martino TA. Circadian Influence on Inflammatory Response During Cardiovascular Disease. Curr Opin Pharmacol (Accepted) 2020
Amgalan D, Garner TP, Pekson P, Yanamandala M, Paulino V, Corbalan JJ, Lee, Scarlata M, Liang H, Narayanagari SW, Mitchell K, Lopez A, Margulets V, Asnani A, Peterson R, Hazan RB, Steidl UG, Kirshenbaum LA, Gavathiotis E, and Kitsis RN. A small-molecule allosteric inhibitor of BAX protects against doxorubicin-induced cardiomyopathy. Nat Cancer 1, 315 – 328; 2020.
Rahaman,P. Del Bigio,M.R. Histology of brain trauma and hypoxia-ischemia. Acad. Forensic Pathol. 8: 539-554, 2018. PMID: 31240058 doi.org/10.1177/1925362118797728 (senior author)
Hartley,J.N. Simard,L.R. Del Bigio,M.R. Ly,V. Frosk,P. A homozygous canonical splice acceptor site mutation in PRUNE 1 is responsible for a rare childhood neurodegenerative disease in Manitoba Cree families. Am. J. Med. Genet. Part A. 179(2):206-218, 2019 PMID: 30556349 (muscle histopathology, autopsy, editing)
Jarmasz,J.S. Stirton,H. Davie,J. Del Bigio,M.R. DNA methylation and histone post-translational modification stability in post-mortem brain tissue. Clin. Epigenetics 11(1):5, 2019. PMID: 30635019 (senior author - funding CIHR)
Jarmasz,J.S. Basalah,D. Davie,J. Clarren,S. Astley,S. Del Bigio,M.R. Global DNA methylation and histone posttranslational modifications in human and nonhuman primate brain in association with prenatal alcohol exposure. Alcoholism Clin. Exp. Res. 43: 1145-1162, 2019 PMID: 31074890 (senior author - funding CIHR)
Wagner,R. Ayoub,L. Kahnamoui,S. Li,H. Patel,D. Liu,D. Del Bigio,M.R. Stefanovici,C. Lacher,M. Keijzer, R. Establishment of a biobank for human lung tissues of congenital diaphragmatic hernia and congenital pulmonary airway malformation. J. Pediatr. Surg. 54:2439-2442, 2019. PMID: 31130348 (co-author; database creation and editing)
Ajisebutu,A. Del Bigio,M.R. Kazina,C.J. West,M. Serletis,D. Dr. Dwight Parkinson: A Canadian Neurosurgical Pioneer. J. Neurosurg. 2019 DOI: 10.3171/2019.6.JNS19262 PMID: 31561217 (biography, collaborator)
Del Bigio,M.R. Sidhu,R. Kazina,C.J. Serletis,D. Distal catheter slit obstructions in ventriculoperitoneal shunts: possible role of graphite in potentiating inflammation. J. Neurosurg. 2019 DOI: 10.3171/2019.6.JNS191082 PMID: 31561214 (senior author)
Lopez,A. Kazina,C. Del Bigio,M.R. Fanella,S. Candida albicans ventriculoperitoneal shunt infection in an infant: A case report and review of the literature. J. Assoc. Med. Microbiol. Infect. Dis. In press 2019 manuscript jammi-2019-0020 (neuropathology evaluation; single case report)
Shabanipour,S. Dalvand,A. Jiao,X. Rahimi Balaei,M. Chung,S.H. Kong,J. Del Bigio,M.R. Marzban,H. Primary culture of neurons isolated from embryonic mouse cerebellum. J. Vis. Exp. 2019 Oct 26;(152). doi: 10.3791/60168 PMID: 31710031 (collaborator; interpretation, editing, narration)
Pejhan,S. Siu,V.M. Ang,L.C. Del Bigio,M.R. Rastegar,M. Differential brain region-specific expression of MeCP2 and BDNF in Rett Syndrome patients; A distinct gray-white matter variation. Neuropathol. Appl. Neurobiol. 2020 Apr 4. doi: 10.1111/nan.12619. Online ahead of print. PMID: 32246495 (collaborator and joint corresponding author; responsible for human tissue interpretation)
Pejhan,S. Del Bigio,M.R. Rastegar,M. The MeCP2E1/E2-BDNF-miR132 homeostasis regulatory network is region-dependent in the human brain and is impaired in Rett syndrome patients. Front. Cell Dev. Biol., 8: 763, 2020 https://doi.org/10.3389/fcell.2020.00763 (collaborator; responsible for human tissue interpretation).
Du,X.Z. Del Bigio,M.R. Stefanovici,C. Miller,E. Fan,C.W. Bunge,M. Rozovsky,K. A case of diprosopus: a rare form of twinning. Case Rep. Perinatal Med. Accepted 2020 January 08, manuscript # CRPM.2019.0068 (case report - neuropathology description)
Peikes,T Chodirker,B Booth,F Del Bigio,M.R. Frosk,P. Homozygous 19q13.42 deletion: a novel autosomal recessive microdeletion syndrome associated with nemaline myopathy and cardiomyopathy discovered in two Mennonite siblings (poster). Canadian College of Medical Geneticists 43rd Annual Scientific Meeting – June 23-25, 2019, Niagara Falls
Del Bigio,M Sidhu,R. Kazina,C. Serletis,D. Graphite deposits are associated with distal catheter obstructions in ventriculoperitoneal shunts for hydrocephalus (Abstract #30). AANP 95th Annual Meeting June 6-9, 2019 Atlanta, Georgia. J Neuropathol Exp Neurol 78:528, 2019.
Kofler,J Pytel,P Del Bigio,M Medina-Flores,R Rugari,A Escolar,M. The Neuropathologic Spectrum of Krabbe Disease (abstract #27). AANP 95th Annual Meeting June 6-9, 2019 Atlanta, Georgia. J Neuropathol Exp Neurol 78:527, 2019.
Del Bigio,M. Spinal nerve root blood in pediatric autopsy cases is a marker of subarachnoid hemorrhage. AANP 96th Annual Meeting June 11-14, 2020 (virtual). J Neuropathol Exp Neurol 79:693, 2020.
Islam,M.I. Pandian,N. Shcholok,T. Contu,F. Mai,S. Albensi,B.C. Del Bigio,M. Park,I.-S. Eftekharpour,E. Lamin B is a substrate of cathepsin L in Alzheimer’s Disease. CHSRF-2020 virtual research day.
Osawa,N. Greenberg,C.R. Zelinski,T. Del Bigio,M.R. Frosk,P. Brain and myelin abnormalities in a family with TBCK mutation. National Society of Genetic Counsellors annual meeting 2020 (virtual).
Book chapters
Nagra,G.* Del Bigio,M.R. Pathology of pediatric hydrocephalus. In: Pediatric Hydrocephalus 2nd edition. G. Cinalli, M.M. Özek, C. Sainte-Rose (eds.) Springer: New York pp. 359-377, 2019 (ISBN 978-3-319-27248-1)